May 2006 Meeting

Retention Mechanisms in Reversed-Phase
Liquid Chromatography: Embedded Polar Group Columns

Annual Meeting

The May 2006 CSSC meeting will be held at 
the Yankee Silversmith Inn in Wallingford, CT.

Dinner:  personal choice, which must be indicated at the time of registration of either:

1. Chicken Asparagus topped with Portobello mushrooms, Roma tomatoes, Scampi style; or

2. Baked Boston Cod, Heritage Style; or

3. Vegetarian Dish - Puff pastry shell with grilled vegetables 

All meals include: 

Appetizer: Chilled Fresh Cut Fruit with Lemon Sherbert
Salad: Silversmith Garden
Dessert: Strawberry Shortcake with homemade biscuit 
Dessert comes with regular coffee, decaffeinated coffee or tea 

The cost of the meeting is $30 ($20 Students and Emeritus),
and is to be paid at the day of the event. 

To register, use our secure online system at Past Deadline.

To use the online system, you must be registered as a user.
Clicking here to become a registered user. 

Click here for a printable version of this announcement

Abstract:

J. McKenzie, D. Bell

Embedded polar group (EPG) stationary phases that contain amide functionalities have become a popular alternative to traditional C18 and C8 phases in modern HPLC method development. Application data has suggested that EPG phases show preferential retention for neutral acidic and phenolic analytes when compared to the more hydrophobic alkyl phases. A popular explanation is that hydrogen bonding plays a significant role in the overall retention mechanism. The purpose of this study was to examine some possible solute retention mechanisms on EPG phases using chromatographic models that attempt to separate and weigh contributions arising from different types of molecular interactions.

Biography:  Jacinth McKenzie received a B.Sc. (Chemistry) and M.Phil. (Organometallic Chemistry) from the University of the West Indies, Mona in Jamaica. She then pursued a Ph.D. in Bioanalytical Chemistry at the University of Florida, Gainesville working in the area of in-vivo amine-neurotransmitter monitoring by capillary LC-EC under the supervision of Robert Kennedy. Upon graduation in 2002, she received a taste of the pharmaceutical industry when she joined the staff at Watson Laboratories in Miami. Currently, she is employed as an applications method development chemist at Sigma-Aldrich/Supelco. Her areas of expertise include HPLC, LC-MS, capillary liquid chromatography, electrochemistry, pharmaceutical testing and neurotransmitter analysis. She has several publications in the areas of synthesis and characterization, chromatography and in-vivo cell signaling. 

Yankee Silversmith Inn
1033 North Colony Road
Wallingford, CT 06492
(203) 269-5444

Last Updated:  05/09/2006 10:48 PM